Wissenschaftliche Publikationen

Ringrose, L. (2017). Noncoding RNAs in Polycomb and Trithorax Regulation: A Quantitative Perspective. Annu Rev Genet. (abstract)
Asaoka, T., Almagro, J., Ehrhardt, C., Tsai, I., Schleiffer, A., Deszcz, L., Junttila, S., Ringrose, L., Mechtler, K., Kavirayani, A., Gyenesei, A., Hofmann, K., Duchek, P., Rittinger, K., Ikeda, F. (2016). Linear ubiquitination by LUBEL has a role in Drosophila heat stress response. EMBO Rep. 17(11):1624-1640 (abstract)
Bauer, M., Trupke, J., Ringrose, L. (2016). The quest for mammalian Polycomb response elements: are we there yet? Chromosoma. 125(3):471-96 (abstract)
Ringrose, L. (2015). Reconciling randomness and precision. Nat Rev Mol Cell Biol. 16(11):642 (abstract)
Herzog, VA., Lempradl, A., Trupke, J., Okulski, H., Altmutter, C., Ruge, F., Boidol, B., Kubicek, S., Schmauss, G., Aumayr, K., Ruf, M., Pospisilik, A., Dimond, A., Senergin, HB., Vargas, ML., Simon, JA., Ringrose, L. (2014). A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet. 46(9):973-81 (abstract)
Steffen, PA., Ringrose, L. (2014). What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory. Nat Rev Mol Cell Biol. 15(5):340-56 (abstract)
Steffen, PA., Fonseca, JP., Gänger, C., Dworschak, E., Kockmann, T., Beisel, C., Ringrose, L. (2013). Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin. Nucleic Acids Res. 41(10):5235-50 (abstract)
Fonseca, JP., Steffen, PA., Müller, S., Lu, J., Sawicka, A., Seiser, C., Ringrose, L. (2012). In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells. Genes Dev. 26(8):857-71 (abstract)
Hekimoglu-Balkan, B., Aszodi, A., Heinen, R., Jaritz, M., Ringrose, L. (2012). Intergenic Polycomb target sites are dynamically marked by non-coding transcription during lineage commitment. RNA Biol. 9(3):314-25 (abstract)
Steffen, PA., Fonseca, JP., Ringrose, L. (2012). Epigenetics meets mathematics: towards a quantitative understanding of chromatin biology. Bioessays. 34(10):901-13 (abstract)
vandenBerg, A., Ringrose, L. (2012). First annual meeting of the EpiGeneSys Network of Excellence: moving epigenetics towards systems biology. Bioessays. 34(7):620-5 (abstract)
Okulski, H., Druck, B., Bhalerao, S., Ringrose, L. (2011). Quantitative analysis of polycomb response elements (PREs) at identical genomic locations distinguishes contributions of PRE sequence and genomic environment. Epigenetics Chromatin. 4:4 (abstract)
Strübbe, G., Popp, C., Schmidt, A., Pauli, A., Ringrose, L., Beisel, C., Paro, R. (2011). Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners. Proc Natl Acad Sci U S A. 108(14):5572-7 (abstract)
Ringrose, L. (2010). How do RNA sequence, DNA sequence, and chromatin properties regulate splicing? F1000 Biol Rep. 2:74 (abstract)
Hekimoglu, B., Ringrose, L. (2009). Non-coding RNAs in polycomb/trithorax regulation. RNA Biol. 6(2):129-37 (abstract)
Ringrose, L. (2009). Transgenesis in Drosophila melanogaster. Methods Mol Biol. 561:3-19 (abstract)
Hauenschild, A., Ringrose, L., Altmutter, C., Paro, R., Rehmsmeier, M. (2008). Evolutionary plasticity of polycomb/trithorax response elements in Drosophila species. PLoS Biol. 6(10):e261 (abstract)
Lempradl, A., Ringrose, L. (2008). How does noncoding transcription regulate Hox genes? Bioessays. 30(2):110-21 (abstract)
Ringrose, L. (2007). Polycomb comes of age: genome-wide profiling of target sites. Curr Opin Cell Biol. 19(3):290-7 (abstract)
Ringrose, L., Paro, R. (2007). Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development. 134(2):223-32 (abstract)
Ringrose, L. (2006). Polycomb, trithorax and the decision to differentiate. Bioessays. 28(4):330-4 (abstract)
Lee, N., Maurange, C., Ringrose, L., Paro, R. (2005). Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs. Nature. 438(7065):234-7 (abstract)
Ringrose, L., Ehret, H., Paro, R. (2004). Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes. Mol Cell. 16(4):641-53 (abstract)
Ringrose, L., Paro, R. (2004). Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet. 38:413-43 (abstract)
Ringrose, L., Rehmsmeier, M., Dura, JM., Paro, R. (2003). Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Dev Cell. 5(5):759-71 (abstract)
Ringrose, L., Paro, R. (2001). Remembering silence. Bioessays. 23(7):566-70 (abstract)
Ringrose, L., Paro, R. (2001). Gene regulation. Cycling silence. Nature. 412(6846):493-4 (abstract)
Ringrose, L., Chabanis, S., Angrand, PO., Woodroofe, C., Stewart, AF. (1999). Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances. EMBO J. 18(23):6630-41 (abstract)
Ringrose, L., Lounnas, V., Ehrlich, L., Buchholz, F., Wade, R., Stewart, AF. (1998). Comparative kinetic analysis of FLP and cre recombinases: mathematical models for DNA binding and recombination. J Mol Biol. 284(2):363-84 (abstract)
Ringrose, L. (1997). Biochemical analysis of the site specific recombinases of yeasts and of bacteriophage P1. PhD thesis, EMBL laboratory.
Ringrose, L., Angrand, PO., Stewart, AF. (1997). The Kw recombinase, an integrase from Kluyveromyces waltii. Eur J Biochem. 248(3):903-12 (abstract)
Buchholz, F., Ringrose, L., Angrand, PO., Rossi, F., Stewart, AF. (1996). Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination. Nucleic Acids Res. 24(21):4256-62 (abstract)

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